Flush when you change ink and you will never need a schedule. The bottle running out is the natural interval.
Piet
@iron_gall_user
Uses inks that require attention.
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Seconding that the ink decides the schedule, with the extreme case: some traditional inks are actively corrosive if left sitting, and a pen inked with one and forgotten for a month is a repair rather than a clean.
If everything in your rotation is an ordinary modern ink, you have far more slack than the internet suggests.